Photograph of an Asian man with short brown hair, eyeglasses, and a blue shirt, standing in front of buildings and trees.
Sehi L'Yi
이세희 / 李世熙

I’m a tenure-track Assistant Professor at the Department of Computer Science and Engineering at the Hong Kong University of Science and Technology. Previously, I was an NIH K99/R00 Pathway to Independence Fellow at the Department of Biomedical Informatics at Harvard Medical School, working with Nils Gehlenborg. I received my PhD in Computer Science and Engineering from Seoul National University with the supervision of Jinwook Seo at the Human-Computer Interaction Lab.

As an interdisciplinary researcher, I work at the intersection of visualization, human–AI interaction, and biomedicine. Current focus areas include ➊ visualization and human–AI interaction for biomedical applications (e.g., healthcare, science, and education), ➋ toolkits and infrastructure for scalable visualization and human–AI interaction, ➌ AI interpretability and model understanding through interactive visualization, and ➍ emerging interaction techniques for complex biomedical data (e.g., VR/AR/MR). For example, I led the design and development of the Gosling visualization grammar, which enables constructing scalable and interactive genomics data visualizations and leveraging AI methods (read Nature’s Technology Feature).

My work has been published in top-tier conferences and journals across my fields, including VIS, TVCG, CHI, UIST, Nature Methods, Bioinformatics, and npj Digital Medicine. I have received several academic awards, including the NIH/NHGRI K99/R00 Pathway to Independence Award, VIS Best Paper Honorable Mention Award, ISMB BioVis Best Abstract Award, ISMB BioVis Runner-Up Abstract Award, and VIS Best Poster Research Award. I have served on the program committee for top visualization conferences, including VIS, EuroVis, and PacificVis.

I'm currently looking to recruit PhD students (Fall'26, Spring'27, Fall'27) at HKUST CSE. For details, please read the Work With Me page.

News [see all]

PAPER Jul 6, 2026
Two Abstracts @ ISMB 2026
Two abstracts on agentic authoring and keyboard accessibility were accepted at ISMB 2026.
NEWS Jun 15, 2026
New Journey @ HKUST CSE
Sehi officially started as an Assistant Professor of Computer Science and Engineering at HKUST.
SERVICE Jan 20, 2026
Program Committee @ VIS 2026
Sehi is serving on the program committee for full papers at IEEE VIS 2026.
PAPER Jan 16, 2026
Visualization Design Knowledge Bases @ CHI 2026
A paper on formalized visualization design knowledge bases was accepted at CHI 2026.

Selected Projects

Visualization Toolkits for Biomedicine
Visualization Toolkits for Biomedicine

Selected Publications [see more]

Hyeok Kim, Sehi L'Yi, Nils Gehlenborg, Jeffrey Heer
In Proceedings of the SIGCHI Conference on Human Factors in Computing Systems (CHI ’26) (2026)
25.3% acceptance rate
Sehi L'Yi, Harrison G. Zhang, Andrew P. Mar, Thomas C. Smits, Lawrence Weru, Sofía Rojas, Alexander Lex, Nils Gehlenborg
Scientific Reports (2025) 15, 23676
Sehi L'Yi, Astrid van den Brandt, Etowah Adams, Huyen N. Nguyen, Nils Gehlenborg
IEEE Transactions on Visualization and Computer Graphics (TVCG) (Proc. VIS) (2025)
23.2% acceptance rate
Best Paper Honorable Mention
Thomas C Smits**, Sehi L'Yi, Andrew Patrick Mar, Nils Gehlenborg
Bioinformatics (2024)
Runner-Up Abstract Award at ISMB BioVis 2025
Sehi L'Yi, Dominika Maziec, Victoria Stevens, Trevor Manz, Alexander Veit, Michele Berselli, Peter J Park, Dominik Głodzik, Nils Gehlenborg
Nature Methods (2023) 20, 1834–1835
Aditeya Pandey**, Sehi L'Yi, Qianwen Wang, Michelle A Borkin, Nils Gehlenborg
IEEE Transactions on Visualization and Computer Graphics (TVCG) (Proc. VIS) (2023) 29(1), 570-580
26.5% acceptance rate
IEEE InfoVis Best Poster Research Award
Sehi L'Yi, Qianwen Wang, Fritz Lekschas, Nils Gehlenborg
IEEE Transactions on Visualization and Computer Graphics (TVCG) (Proc. VIS) (2022) 28(1), 40-150
25.8% acceptance rate
ISMB/ECCB BioVis Best Abstract Award

Media Coverage

Nature (TECHNOLOGY FEATURE)
Powerful 'grammar' allows geneticists to display their data in interactive and scalable illustrations.
"Postdoc Sehi L'Yi, who led Gosling's development, says that what differentiates Gosling from other visualization tools is its expressiveness. With most tools, he says, the graphics that can be made and what they will look like are predefined. 'It is really not easy to customize visualizations as a user.' But with Gosling, users can, for instance, specify the colour, dimensions and placement of the symbol used to represent a centromere or genomic interval, then overlay that on an ideogram of a chromosome to highlight a region of interest."
Image with two heatmap visualizations that look like an eyebrow and an eye.